Identification and Characterization of a Novel Small-Molecule Inhibitor of β-Catenin Signaling

Hepatocellular carcinoma (HCC), the third most common cause of cancer-related deaths worldwide, lacks effective medical therapy. Large subsets of HCC demonstrate Wnt/β-catenin activation, making this an attractive therapeutic target. We report strategy and characterization of a novel small-molecule...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Delgado, Evan R., Yang, Jing, So, Juhoon, Leimgruber, Stephanie, Kahn, Michael, Ishitani, Tohru, Shin, Donghun, Mustata Wilson, Gabriela, Monga, Satdarshan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076560/
https://ncbi.nlm.nih.gov/pubmed/24819961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.04.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados