Tubular Obstruction Leads to Progressive Proximal Tubular Injury and Atubular Glomeruli in Polycystic Kidney Disease

In polycystic kidney disease (PKD), renal parenchyma is destroyed by cysts, hypothesized to obstruct nephrons. A signature of unilateral ureteral obstruction, proximal tubular atrophy leads to formation of atubular glomeruli. To determine whether this process occurs in PKD, kidneys from pcy mice (mo...

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Detalhes bibliográficos
Main Authors: Galarreta, Carolina I., Grantham, Jared J., Forbes, Michael S., Maser, Robin L., Wallace, Darren P., Chevalier, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076474/
https://ncbi.nlm.nih.gov/pubmed/24815352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.007
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