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IL-19 Reduces Ligation-Mediated Neointimal Hyperplasia by Reducing Vascular Smooth Muscle Cell Activation

We tested the hypothesis that IL-19, a putative member of the type 2 helper T-cell family of anti-inflammatory interleukins, can attenuate intimal hyperplasia and modulate the vascular smooth muscle cell (VSMC) response to injury. Ligated carotid artery of IL-19 knockout (KO) mice demonstrated a sig...

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Autors principals: Ellison, Stephen, Gabunia, Khatuna, Richards, James M., Kelemen, Sheri E., England, Ross N., Rudic, Dan, Azuma, Yasu-Taka, Munroy, M. Alexandra, Eguchi, Satoru, Autieri, Michael V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076471/
https://ncbi.nlm.nih.gov/pubmed/24814101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.04.001
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