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Phosphodiesterase-3 inhibitor (cilostazol) attenuates oxidative stress-induced mitochondrial dysfunction in the heart

BACKGROUND: Cilostazol is a type 3 phosphodiesterase inhibitor which has been previously demonstrated to prevent the occurrence of tachyarrhythmia and improve defibrillation efficacy. However, the mechanism for this beneficial effect is still unclear. Since cardiac mitochondria have been shown to pl...

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Главные авторы: Chattipakorn, Siriporn C., Thummasorn, Savitree, Sanit, Jantira, Chattipakorn, Nipon
Формат: Artigo
Язык:Inglês
Опубликовано: Science Press 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076456/
https://ncbi.nlm.nih.gov/pubmed/25009566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3969/j.issn.1671-5411.2014.02.014
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