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Inhibitory Effect of Progesterone on Cervical Tissue Formation in a Three-Dimensional Culture System with Human Cervical Fibroblasts

Progesterone supplementation is recommended to prevent preterm birth in women with a short cervix, but the mechanism is unclear. We hypothesize that progesterone acts by altering the composition of the cervical extracellular matrix (ECM). We tested this hypothesis using human cervical fibroblasts in...

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Autores principales: House, Michael, Tadesse-Telila, Serkalem, Norwitz, Errol R., Socrate, Simona, Kaplan, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076401/
https://ncbi.nlm.nih.gov/pubmed/24285720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.112540
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