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Inhibitory Effect of Progesterone on Cervical Tissue Formation in a Three-Dimensional Culture System with Human Cervical Fibroblasts

Progesterone supplementation is recommended to prevent preterm birth in women with a short cervix, but the mechanism is unclear. We hypothesize that progesterone acts by altering the composition of the cervical extracellular matrix (ECM). We tested this hypothesis using human cervical fibroblasts in...

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Autori principali: House, Michael, Tadesse-Telila, Serkalem, Norwitz, Errol R., Socrate, Simona, Kaplan, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for the Study of Reproduction, Inc. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076401/
https://ncbi.nlm.nih.gov/pubmed/24285720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.112540
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