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Using beta binomials to estimate classification uncertainty for ensemble models

BACKGROUND: Quantitative structure-activity (QSAR) models have enormous potential for reducing drug discovery and development costs as well as the need for animal testing. Great strides have been made in estimating their overall reliability, but to fully realize that potential, researchers and regul...

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Detalhes bibliográficos
Main Authors: Clark, Robert D, Liang, Wenkel, Lee, Adam C, Lawless, Michael S, Fraczkiewicz, Robert, Waldman, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076254/
https://ncbi.nlm.nih.gov/pubmed/24987464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-6-34
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