Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2

Platelet-activating factor (PAF) is a potent pro-inflammatory phospholipid mediator. In response to extracellular stimuli, PAF is rapidly biosynthesized by lyso-PAF acetyltransferase (lyso-PAFAT). Previously, we identified two types of lyso-PAFATs: lysophosphatidylcholine acyltransferase (LPCAT)1, m...

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Detalhes bibliográficos
Main Authors: Tarui, Megumi, Shindou, Hideo, Kumagai, Kazuo, Morimoto, Ryo, Harayama, Takeshi, Hashidate, Tomomi, Kojima, Hirotatsu, Okabe, Takayoshi, Nagano, Tetsuo, Nagase, Takahide, Shimizu, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076079/
https://ncbi.nlm.nih.gov/pubmed/24850807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049205
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