Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice

Nonalcoholic fatty liver disease is a major public health concern in the obese and type 2 diabetic populations. The high-fat lard diet induces obesity and fatty liver in C57BL/6J mice and suppresses expression of the PPAR-target gene, FA elongase 5 (Elovl5). Elovl5 plays a key role in MUFA and PUFA...

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Bibliografiske detaljer
Main Authors: Tripathy, Sasmita, Lytle, Kelli A., Stevens, Robert D., Bain, James R., Newgard, Christopher B., Greenberg, Andrew S., Huang, Li-Shin, Jump, Donald B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076069/
https://ncbi.nlm.nih.gov/pubmed/24814977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050062
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