Inositol Phosphate Recycling Regulates Glycolytic and Lipid Metabolism That Drives Cancer Aggressiveness

[Image: see text] Cancer cells possess fundamentally altered metabolism that supports their pathogenic features, which includes a heightened reliance on aerobic glycolysis to provide precursors for synthesis of biomass. We show here that inositol polyphosphate phosphatase 1 (INPP1) is highly express...

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Autors principals: Benjamin, Daniel I., Louie, Sharon M., Mulvihill, Melinda M., Kohnz, Rebecca A., Li, Daniel S., Chan, Lauryn G., Sorrentino, Antonio, Bandyopadhyay, Sourav, Cozzo, Alyssa, Ohiri, Anayo, Goga, Andrei, Ng, Shu-Wing, Nomura, Daniel K.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076040/
https://ncbi.nlm.nih.gov/pubmed/24738946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5001907
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