Ultrasmall Gold Nanoparticles as Carriers for Nucleus-Based Gene Therapy Due to Size-Dependent Nuclear Entry

[Image: see text] The aim of this study was to determine the size-dependent penetration ability of gold nanoparticles and the potential application of ultrasmall gold nanoparticles for intranucleus delivery and therapy. We synthesized gold nanoparticles with diameters of 2, 6, 10, and 16 nm and comp...

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Autores principales: Huo, Shuaidong, Jin, Shubin, Ma, Xiaowei, Xue, Xiangdong, Yang, Keni, Kumar, Anil, Wang, Paul C., Zhang, Jinchao, Hu, Zhongbo, Liang, Xing-Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076024/
https://ncbi.nlm.nih.gov/pubmed/24824865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn5008572
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