Dietary α-mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice

SCOPE: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon. α-Mangostin (α-MG), the most abundant xanthone in mangosteen fruit, exerts anti-inflammatory and antibacterial activities in vitro. We evaluated the impact of dietary α-MG on murine experimental colitis and on the gut mic...

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Main Authors: Gutierrez-Orozco, Fabiola, Thomas-Ahner, Jennifer M., Berman-Booty, Lisa D., Galley, Jeffrey D., Chitchumroonchokchai, Chureeporn, Mace, Thomas, Suksamrarn, Sunit, Bailey, Michael T., Clinton, Steven K., Lesinski, Gregory B., Failla, Mark L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076011/
https://ncbi.nlm.nih.gov/pubmed/24668769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201300771
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