Hsp70 - a biomarker for tumor detection and monitoring of outcome of radiation therapy in patients with squamous cell carcinoma of the head and neck

BACKGROUND: Tumor but not normal cells frequently overexpress heat shock protein 70 (Hsp70) and present it on their cell surface (mHsp70) from where it can be actively released. Therefore, membrane (mHsp70) and soluble Hsp70 (sHsp70) were investigated as potential tumor biomarkers and for monitoring...

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Main Authors: Gehrmann, Mathias, Specht, Hanno M, Bayer, Christine, Brandstetter, Markus, Chizzali, Barbara, Duma, Marciana, Breuninger, Stephanie, Hube, Kathrin, Lehnerer, Sophie, van Phi, Valerie, Sage, Eva, Schmid, Thomas E, Sedelmayr, Michael, Schilling, Daniela, Sievert, Wolfgang, Stangl, Stefan, Multhoff, Gabriele
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075935/
https://ncbi.nlm.nih.gov/pubmed/24912482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-9-131
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