Metformin synergistically enhances antiproliferative effects of cisplatin and etoposide in NCI-H460 human lung cancer cells

OBJECTIVE: To test the effectiveness of combining conventional antineoplastic drugs (cisplatin and etoposide) with metformin in the treatment of non-small cell lung cancer in the NCI-H460 cell line, in order to develop new therapeutic options with high efficacy and low toxicity. METHODS: We used the...

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Autori principali: Teixeira, Sarah Fernandes, Guimarães, Isabella dos Santos, Madeira, Klesia Pirola, Daltoé, Renata Dalmaschio, Silva, Ian Victor, Rangel, Leticia Batista Azevedo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Sociedade Brasileira de Pneumologia e Tisiologia 2013
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075897/
https://ncbi.nlm.nih.gov/pubmed/24473757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1806-37132013000600002
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