Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease

AIM: To investigate the effects of diosgenin (Dio), a naturally occurring steroid saponin, on goiter formation in a mouse model of Graves' disease (GD) and the underlying mechanisms. METHODS: Female BALB/c mice were injected with adenovirus expressing the A subunit of thyrotropin receptor to in...

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Main Authors: Cai, Hu, Wang, Zhe, Zhang, Hai-qing, Wang, Fu-rong, Yu, Chun-xiao, Zhang, Feng-xia, Gao, Ling, Zhang, Jian, Zhao, Jia-jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075739/
https://ncbi.nlm.nih.gov/pubmed/24241350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.133
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