The bacterial protein toxin, cytotoxic necrotizing factor 1 (CNF1) provides long-term survival in a murine glioma model

BACKGROUND: Glioblastomas are largely unresponsive to all available treatments and there is therefore an urgent need for novel therapeutics. Here we have probed the antineoplastic effects of a bacterial protein toxin, the cytotoxic necrotizing factor 1 (CNF1), in the syngenic GL261 glioma cell model...

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Autores principales: Vannini, Eleonora, Panighini, Anna, Cerri, Chiara, Fabbri, Alessia, Lisi, Simonetta, Pracucci, Enrico, Benedetto, Nicola, Vannozzi, Riccardo, Fiorentini, Carla, Caleo, Matteo, Costa, Mario
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075618/
https://ncbi.nlm.nih.gov/pubmed/24939046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-449
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