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Effect on therapeutic ratio of planning a boosted radiotherapy dose to the dominant intraprostatic tumour lesion within the prostate based on multifunctional MR parameters

OBJECTIVE: To demonstrate the feasibility of an 8-Gy focal radiation boost to a dominant intraprostatic lesion (DIL), identified using multiparametric MRI (mpMRI), and to assess the potential outcome compared with a uniform 74-Gy prostate dose. METHODS: The DIL location was predicted in 23 patients...

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Autori principali: Riches, S F, Payne, G S, deSouza, N M, Dearnaley, D, Morgan, V A, Morgan, S C, Partridge, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: The British Institute of Radiology. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075537/
https://ncbi.nlm.nih.gov/pubmed/24601648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20130813
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