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Developmental insights from early mammalian embryos and core signaling pathways that influence human pluripotent cell growth and differentiation

Human pluripotent stem cells (hPSCs) have two potentially attractive applications: cell replacement-based therapies and drug discovery. Both require the efficient generation of large quantities of clinical-grade stem cells that are free from harmful genomic alterations. The currently employed colony...

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Autors principals: Chen, Kevin G., Mallon, Barbara S., Johnson, Kory R., Hamilton, Rebecca S., McKay, Ronald D.G., Robey, Pamela G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075444/
https://ncbi.nlm.nih.gov/pubmed/24603366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2014.02.002
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