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Autophagy Promotes Primary Ciliogenesis by Removing OFD1 from Centriolar Satellites

The primary cilium is a microtubule-based organelle that functions in sensory and signaling pathways. Defects in ciliogenesis can lead to a group of genetic syndromes known as ciliopathies(1–3). However, the regulatory mechanisms of primary ciliogenesis in normal and cancer cells are incompletely un...

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Hlavní autoři: Tang, Zaiming, Lin, Mary Grace, Stowe, Timothy R., Chen, She, Zhu, Muyuan, Stearns, Tim, Franco, Brunella, Zhong, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075283/
https://ncbi.nlm.nih.gov/pubmed/24089205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12606
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