Fibulin-2 deficiency attenuates angiotensin II-induced cardiac hypertrophy by reducing transforming growth factor-β signalling

AngII (angiotensin II) is a potent neurohormone responsible for cardiac hypertrophy, in which TGF (transforming growth factor)-β serves as a principal downstream mediator. We recently found that ablation of fibulin-2 in mice attenuated TGF-β signalling, protected mice against progressive ventricular...

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Bibliografische gegevens
Hoofdauteurs: ZHANG, Hangxiang, Wu, Jing, DONG, Hailong, KHAN, Shaukat A., CHU, Mon-Li, TSUDA, Takeshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075193/
https://ncbi.nlm.nih.gov/pubmed/23841699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120636
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