Limited Evidence for Adaptive Evolution and Functional Effect of Allelic Variation at rs702424 in the Promoter of the TAS2R16 Bitter Taste Receptor Gene in Africa

Bitter taste perception, mediated by receptors encoded by the TAS2R loci, plays important roles in human health and nutrition. Prior studies have demonstrated that nonsynonymous variation at site 516 in the coding exon of TAS2R16, a bitter taste receptor gene on chromosome 7, has been subject to pos...

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Autors principals: Campbell, Michael C., Ranciaro, Alessia, Zinshteyn, Daniel, Rawlings-Goss, Renata, Hirbo, Jibril, Thompson, Simon, Woldemeskel, Dawit, Froment, Alain, Omar, Sabah A., Bodo, Jean-Marie, Nyambo, Thomas, Belay, Gurja, Drayna, Dennis, Breslin, Paul A.S., Tishkoff, Sarah A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075171/
https://ncbi.nlm.nih.gov/pubmed/24785689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2014.29
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