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Lymphoblastic Cell Lines in Pharmacogenomics: How applicable are they in clinical outcomes?

LCLs are widely used in pharmacogenomic studies and the applicability of LCLs for various clinical phenotypes is emerging. Early studies have yielded promising results for LCLs as a proxy for genetic variants for treatment outcome for a number of cancers as well as toxicity in varying tissue types i...

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Detalhes bibliográficos
Main Authors: Stark, Amy L., Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075127/
https://ncbi.nlm.nih.gov/pubmed/23556440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.32
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