Osthole Attenuates Doxorubicin-Induced Apoptosis in PC12 Cells through Inhibition of Mitochondrial Dysfunction and ROS Production

Doxorubicin (DOX) is a potent, broad-spectrum chemotherapeutic drug used for treatment of several types of cancers. Despite its effectiveness, it has a wide range of toxic side effects, many of which most likely result from its inherent prooxidant activity. It has been reported that DOX has toxic ef...

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Main Authors: Shokoohinia, Yalda, Hosseinzadeh, Leila, Moieni-Arya, Maryam, Mostafaie, Ali, Mohammadi-Motlagh, Hamid-Reza
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075090/
https://ncbi.nlm.nih.gov/pubmed/25013759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/156848
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