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Comparative Evaluation of Cytotoxic and Apoptogenic Effects of Several Coumarins on Human Cancer Cell Lines: Osthole Induces Apoptosis in p53-Deficient H1299 Cells

Natural products are excellent resources for finding lead structures for the development of chemotherapeutic agents. Coumarins are a class of natural compounds found in a variety of plants. In this study, we evaluated the cytotoxic potential of coumarins isolated from Prangos ferulacea (L.) Lindl. i...

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Autores principales: Yalda Shokoohinia, Leila Hosseinzadeh, Maryam Alipour, Ali Mostafaie, Hamid-Reza Mohammadi-Motlagh
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Limited 2014-01-01
Colección:Advances in Pharmacological Sciences
Acceso en línea:http://dx.doi.org/10.1155/2014/847574
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