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Applications of NMR-based PRE and EPR-based DEER Spectroscopy to Homodimer Chain Exchange Characterization and Structure Determination

The success of homodimer structure determination by conventional solution NMR spectroscopy relies greatly on interchain distance restraints (less than 6 Å) derived from nuclear Overhauser effects (NOEs) obtained from (13)C-edited, (12)C-filtered NOESY experiments. However, these experiments may fail...

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Detalhes bibliográficos
Main Authors: Yang, Yunhuang, Ramelot, Theresa A., Ni, Shuisong, McCarrick, Robert M., Kennedy, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075034/
https://ncbi.nlm.nih.gov/pubmed/24203336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-691-7_16
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