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Interdependence of Muscle Atrophy and Bone Loss Induced by Mechanical Unloading

Mechanical unloading induces muscle atrophy and bone loss; however, the time course and interdependence of these effects is not well defined. We subjected 4-month-old C57BL/6J mice to hindlimb suspension (HLS) for three weeks, sacrificing 12-16 mice on day (D) 0, 7, 14, and 21. Lean mass was 7-9% lo...

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Detalles Bibliográficos
Main Authors: Lloyd, Shane A., Lang, Charles H., Zhang, Yue, Paul, Emmanuel M., Laufenberg, Lacee J., Lewis, Gregory S., Donahue, Henry J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074925/
https://ncbi.nlm.nih.gov/pubmed/24127218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2113
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