Pharmacokinetics, Electrophysiological, and Morphological Effects of the Intravitreal Injection of Mycophenolic Acid in Rabbits

Purpose: To determine the half-life of mycophenolic acid (MPA) in the vitreous of New Zealand albino rabbits after intravitreal injection and the retinal toxicity of different doses of MPA. Methods: Ten micrograms of MPA (Roche Bioscience, Palo Alto, CA) was injected in the vitreous of 16 rabbits, a...

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Detalhes bibliográficos
Main Authors: Gasparin, Fabio, Aguiar, Renata Genaro, Ioshimoto, Gabriela Lourençon, Silva-Cunha, Armando, Fialho, Silvia Ligório, Liber, André Mauricio, Nagy, Balázs Vince, Oiwa, Nestor Norio, Costa, Marcelo Fernandes, Joselevitch, Christina, Ventura, Dora Fix, Damico, Francisco Max
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074757/
https://ncbi.nlm.nih.gov/pubmed/24828287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2013.0236
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