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p53 Modulates Hsp90 ATPase Activity and Regulates Aryl Hydrocarbon Receptor Signaling
The aryl hydrocarbon receptor (AhR), a client protein of heat shock protein 90 (Hsp90), is a ligand activated transcription factor that plays a role in polycyclic aromatic hydrocarbon (PAH) induced carcinogenesis. Tobacco smoke activates AhR signaling leading to increased transcription of CYP1A1 and...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074578/ https://ncbi.nlm.nih.gov/pubmed/24736433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0051 |
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