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A single misstep in cardiac development explains the co-occurrence of tetralogy of Fallot and complete atrioventricular septal defect in Down syndrome
Tetralogy of Fallot and a complete atrioventricular septal defect are thought to arise by distinct mechanisms, yet their co-occurrence is a recognized association. Analysis of the prevalence of co-occurrence in Down syndrome suggests a common developmental basis. Trisomy 21 may perturb cardiac proge...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074567/ https://ncbi.nlm.nih.gov/pubmed/24721467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2014.02.065 |
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