Higher FOXP3-TSDR demethylation rates in adjacent normal tissues in patients with colon cancer were associated with worse survival

BACKGROUND: The influence of natural regulatory T cells (nTregs) on the patients with colon cancer is unclear. Demethylated status of the Treg-specific demethylated region (TSDR) of the FOXP3 gene was reported to be a potential biomarker for the identification of nTregs. METHODS: The demethylation r...

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Bibliographische Detailangaben
Hauptverfasser: Zhuo, Changhua, Li, Zhiyuan, Xu, Ye, Wang, Yuwei, Li, Qingguo, Peng, Junjie, Zheng, Hongtu, Wu, Peng, Li, Bin, Cai, Sanjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074420/
https://ncbi.nlm.nih.gov/pubmed/24938080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-153
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