Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal

Hematopoietic stem cells (HSCs) are identified by their ability to sustain prolonged blood cell production in vivo, although recent evidence suggests that durable self-renewal (DSR) is shared by HSC subtypes with distinct self-perpetuating differentiation programs. Net expansions of DSR-HSCs occur i...

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Main Authors: Wohrer, Stefan, Knapp, David J.H.F., Copley, Michael R., Benz, Claudia, Kent, David G., Rowe, Keegan, Babovic, Sonja, Mader, Heidi, Oostendorp, Robert A.J., Eaves, Connie J.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074342/
https://ncbi.nlm.nih.gov/pubmed/24910437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.014
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