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Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunction

Mitochondria are essential organelles producing most of the energy required for the cell. A selective autophagic process called mitophagy removes damaged mitochondria, which is critical for proper cellular homeostasis; dysfunctional mitochondria can generate excess reactive oxygen species that can f...

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Autors principals: Deffieu, Maika, Bhatia-Kiššová, Ingrid, Salin, Bénédicte, Klionsky, Daniel J., Pinson, Benoît, Manon, Stéphen, Camougrand, Nadine
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074285/
https://ncbi.nlm.nih.gov/pubmed/23230142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.103713
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