The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans

Cell migration and axon guidance require proper regulation of the actin cytoskeleton in response to extracellular guidance cues. Rho/Rac small GTPases are essential regulators of actin remodeling. Caenorhabditis elegans CED-10 is a Rac1 homolog that is required for various cellular morphological cha...

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Autors principals: Doi, Motomichi, Minematsu, Hideki, Kubota, Yukihiko, Nishiwaki, Kiyoji, Miyamoto, Masaaki
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074257/
https://ncbi.nlm.nih.gov/pubmed/23900541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.089722
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