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Separate and combined impact of acute naltrexone and alprazolam on subjective and physiological effects of oral d-amphetamine in stimulant users

RATIONALE: Opioid antagonists (e.g., naltrexone) and positive modulators of γ-aminobutyric-acid(A) (GABA(A)) receptors (e.g., alprazolam) modestly attenuate the abuse-related effects of stimulants like amphetamine. The use of higher doses to achieve greater efficacy is precluded by side effects. Com...

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Detalhes bibliográficos
Main Authors: Marks, Katherine R., Lile, Joshua A., Stoops, William W., Rush, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074228/
https://ncbi.nlm.nih.gov/pubmed/24464531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3449-x
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