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Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription

Thyroid hormone (TH) exerts its effects by binding to the thyroid hormone receptor (TR), which binds to TH response elements (TREs) to regulate target gene expression. We investigated the relative ability of liganded homodimers TR and retinoid X receptor (RXR), and the heterodimer TR/RXR, to regulat...

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Detalhes bibliográficos
Main Authors: Paquette, Martin A., Atlas, Ella, Wade, Mike G., Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074170/
https://ncbi.nlm.nih.gov/pubmed/24971931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101155
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