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Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription

Thyroid hormone (TH) exerts its effects by binding to the thyroid hormone receptor (TR), which binds to TH response elements (TREs) to regulate target gene expression. We investigated the relative ability of liganded homodimers TR and retinoid X receptor (RXR), and the heterodimer TR/RXR, to regulat...

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Autors principals: Paquette, Martin A., Atlas, Ella, Wade, Mike G., Yauk, Carole L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074170/
https://ncbi.nlm.nih.gov/pubmed/24971931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101155
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