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Modeling Glial Contributions to Seizures and Epileptogenesis: Cation-Chloride Cotransporters in Drosophila melanogaster

Flies carrying a kcc loss-of-function mutation are more seizure-susceptible than wild-type flies. The kcc gene is the highly conserved Drosophila melanogaster ortholog of K(+)/Cl(−) cotransporter genes thought to be expressed in all animal cell types. Here, we examined the spatial and temporal requi...

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Bibliografiske detaljer
Main Authors: Rusan, Zeid M., Kingsford, Olivia A., Tanouye, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074161/
https://ncbi.nlm.nih.gov/pubmed/24971529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101117
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