Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

Tau is a microtubule-associated protein that aggregates in neurodegenerative disorders known as tauopathies. Recently, studies have suggested that Tau may be secreted and play a role in neural network signalling. However, once deregulated, secreted Tau may also participate in the spreading of Tau pa...

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Главные авторы: Dujardin, Simon, Bégard, Séverine, Caillierez, Raphaëlle, Lachaud, Cédrick, Delattre, Lucie, Carrier, Sébastien, Loyens, Anne, Galas, Marie-Christine, Bousset, Luc, Melki, Ronald, Aurégan, Gwennaëlle, Hantraye, Philippe, Brouillet, Emmanuel, Buée, Luc, Colin, Morvane
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074092/
https://ncbi.nlm.nih.gov/pubmed/24971751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100760
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