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Genetically manipulated mouse models of lung disease: potential and pitfalls

Gene targeting in mice (transgenic and knockout) has provided investigators with an unparalleled armamentarium in recent decades to dissect the cellular and molecular basis of critical pathophysiological states. Fruitful information has been derived from studies using these genetically engineered mi...

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Detalhes bibliográficos
Main Authors: Baron, Rebecca M., Choi, Alexander J. S., Owen, Caroline A., Choi, Augustine M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074003/
https://ncbi.nlm.nih.gov/pubmed/22198907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00085.2011
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