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Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs

Thick ascending limbs (TAL) reabsorb 30% of the filtered NaCl load. Na enters the cells via apical Na-K-2Cl cotransporters and Na/H exchangers and exits via basolateral Na pumps. Chronic angiotensin II (ANG II) infusion increases net TAL Na transport and Na apical entry; however, little is known abo...

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Detalhes bibliográficos
Main Authors: Gonzalez-Vicente, Agustin, Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073928/
https://ncbi.nlm.nih.gov/pubmed/23986517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00064.2013
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