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Target DNA detection and quantitation on a single cell with single base resolution
In this report, we present a new method for sensitive detection of short DNA sites in single cells with single base resolution. The method combines peptide nucleic acid (PNA) openers as the tagging probes, together with isothermal rolling circle amplification (RCA) and fluorescence-based detection,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073798/ https://ncbi.nlm.nih.gov/pubmed/24977169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S2339547813500088 |
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