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A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burger, Alexa, Vasilyev, Aleksandr, Tomar, Ritu, Selig, Martin K., Nielsen, G. Petur, Peterson, Randall T., Drummond, Iain A., Haber, Daniel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Limited 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073279/
https://ncbi.nlm.nih.gov/pubmed/24311731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013128
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