PDE9A is expressed in the inner retina and contributes to the normal shape of the photopic ERG waveform

The ubiquitous second messenger cGMP is synthesized by guanylyl cyclase and hydrolyzed by phosphodiesterase (PDE). cGMP mediates numerous signaling pathways in multiple tissues. In the retina, cGMP regulates signaling in nearly every cell class including photoreceptors, bipolar cells, amacrine cells...

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Bibliographic Details
Main Authors: Dhingra, Anuradha, Tummala, Shanti R., Lyubarsky, Arkady, Vardi, Noga
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073215/
https://ncbi.nlm.nih.gov/pubmed/25018695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00060
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