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Kernel-Machine Testing Coupled with a Rank-Truncation Method for Genetic Pathway Analysis

Traditional genome-wide association studies (GWASs) usually focus on single-marker analysis, which only accesses marginal effects. Pathway analysis, on the other hand, considers biological pathway-gene-marker hierarchical structure and therefore provides additional insights into the genetic architec...

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Hlavní autoři: Yan, Qi, Tiwari, Hemant K., Yi, Nengjun, Lin, Wan-Yu, Gao, Guimin, Lou, Xiang-Yang, Cui, Xiangqin, Liu, Nianjun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073214/
https://ncbi.nlm.nih.gov/pubmed/24849109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21813
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