Attenuation of Skeletal Muscle and Renal Injury to the Lower Limb following Ischemia-Reperfusion Using mPTP Inhibitor NIM-811

INTRODUCTION: Operation on the infrarenal aorta and large arteries of the lower extremities may cause rhabdomyolysis of the skeletal muscle, which in turn may induce remote kidney injury. NIM-811 (N-metyl-4-isoleucine-cyclosporine) is a mitochondria specific drug, which can prevent ischemic-reperfus...

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Main Authors: Garbaisz, David, Turoczi, Zsolt, Aranyi, Peter, Fulop, Andras, Rosero, Oliver, Hermesz, Edit, Ferencz, Agnes, Lotz, Gabor, Harsanyi, Laszlo, Szijarto, Attila
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072765/
https://ncbi.nlm.nih.gov/pubmed/24968303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101067
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