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Macrophage Depletion by Free Bisphosphonates and Zoledronate-Loaded Red Blood Cells

Bisphosphonates, besides being important drugs for the treatment of various bone diseases, could also be used to induce apoptosis in macrophage-like and cancer cells. However, their activity in vivo is limited by a short plasma half-life and rapid uptake within bone. Therefore, several delivery syst...

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Main Authors: Sabatino, Raffaella, Antonelli, Antonella, Battistelli, Serafina, Schwendener, Reto, Magnani, Mauro, Rossi, Luigia
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072741/
https://ncbi.nlm.nih.gov/pubmed/24968029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101260
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