Mycobacteria Counteract a TLR-Mediated Nitrosative Defense Mechanism in a Zebrafish Infection Model

Pulmonary tuberculosis (TB), caused by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb), is a major world health problem. The production of reactive nitrogen species (RNS) is a potent cytostatic and cytotoxic defense mechanism against intracellular pathogens. Nevertheless, the p...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Elks, Philip M., van der Vaart, Michiel, van Hensbergen, Vincent, Schutz, Esther, Redd, Michael J., Murayama, Emi, Spaink, Herman P., Meijer, Annemarie H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072692/
https://ncbi.nlm.nih.gov/pubmed/24967596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100928
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