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Batch Effect Confounding Leads to Strong Bias in Performance Estimates Obtained by Cross-Validation
BACKGROUND: With the large amount of biological data that is currently publicly available, many investigators combine multiple data sets to increase the sample size and potentially also the power of their analyses. However, technical differences (“batch effects”) as well as differences in sample com...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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Public Library of Science
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4072626/ https://ncbi.nlm.nih.gov/pubmed/24967636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100335 |
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