Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma

Varying concentrations of lipopolysaccharide (LPS) in ovalbumin (OVA) may influence the airway response to allergic sensitization and challenge. We assessed the contribution of LPS to allergic airway inflammatory responses following challenge with LPS-rich and LPS-free commercial OVA. BALB/c mice we...

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Main Authors: Mac Sharry, John, Shalaby, Karim H., Marchica, Cinzia, Farahnak, Soroor, Chieh-Li, Tien, Lapthorne, Susan, Qureshi, Salman T., Shanahan, Fergus, Martin, James G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072597/
https://ncbi.nlm.nih.gov/pubmed/24968337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098648
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