Abnormal Type I Collagen Post-translational Modification and Crosslinking in a Cyclophilin B KO Mouse Model of Recessive Osteogenesis Imperfecta

Cyclophilin B (CyPB), encoded by PPIB, is an ER-resident peptidyl-prolyl cis-trans isomerase (PPIase) that functions independently and as a component of the collagen prolyl 3-hydroxylation complex. CyPB is proposed to be the major PPIase catalyzing the rate-limiting step in collagen folding. Mutatio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cabral, Wayne A., Perdivara, Irina, Weis, MaryAnn, Terajima, Masahiko, Blissett, Angela R., Chang, Weizhong, Perosky, Joseph E., Makareeva, Elena N., Mertz, Edward L., Leikin, Sergey, Tomer, Kenneth B., Kozloff, Kenneth M., Eyre, David R., Yamauchi, Mitsuo, Marini, Joan C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072593/
https://ncbi.nlm.nih.gov/pubmed/24968150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004465
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