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Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

The key player in directing proper chromosome segregation is the macromolecular kinetochore complex, which mediates DNA–microtubule interactions. Previous studies testing individual kinetochore genes documented examples of their overexpression in tumors relative to normal tissue, leading to proposal...

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Главные авторы: Thiru, Prathapan, Kern, David M., McKinley, Kara L., Monda, Julie K., Rago, Florencia, Su, Kuan-Chung, Tsinman, Tonia, Yarar, Defne, Bell, George W., Cheeseman, Iain M.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072572/
https://ncbi.nlm.nih.gov/pubmed/24829384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0837
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