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Mechanistic, Mathematical Model to Predict the Dynamics of Tissue Genesis in Bone Defects via Mechanical Feedback and Mediation of Biochemical Factors

The link between mechanics and biology in the generation and the adaptation of bone has been well studied in context of skeletal development and fracture healing. Yet, the prediction of tissue genesis within - and the spatiotemporal healing of - postnatal defects, necessitates a quantitative evaluat...

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Detalhes bibliográficos
Main Authors: Moore, Shannon R., Saidel, Gerald M., Knothe, Ulf, Knothe Tate, Melissa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072518/
https://ncbi.nlm.nih.gov/pubmed/24967742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003604
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